Similarity of relaxations evoked by BRL 34915, pinacidil and field-stimulation in rat oesophageal tunica muscularis mucosae
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چکیده
منابع مشابه
Muscularis mucosae - the forgotten sibling.
Lamina muscularis mucosae sitting beneath mucosal surface of the digestive tract has received little attention to date compared with external smooth muscle layers. Motor activity of the muscularis mucosae shows a great regional and species difference. Autonomic innervation profile is also different from esophagus to colon or between animal species. Intracellular transduction mechanisms for moto...
متن کاملAntigenic Profile of Muscularis Mucosae and Muscularis Propria of the Urinary Bladder
Background: Differentiation between the muscularis mucosae (MM) and muscularispropria (MP) of the bladder remains challenging. Objective: To identify MM- and MP-specific antigens that could be of potential value for staging of urothelialcarcinomain a pilot study. Method: The expression of 12 protein antigens in 11 human bladder specimens was examined. There were 5 post radical cystectomy specim...
متن کاملEffects of drugs and of electrical stimulation on the muscularis mucosae of rabbit large intestine.
1. The muscularis mucosae of the rabbit large intestine shows spontaneous rhythmic contractions with an average frequency of about 11/minute.2. The muscularis mucosae responds to acetylcholine, adrenaline and noradrenaline in a manner similar to that of whole segments of terminal large intestine.3. The muscularis mucosae would seem to have a cholinergic motor innervation.
متن کاملMuscularis mucosae contraction evokes colonic secretion via prostaglandin synthesis and nerve stimulation.
This in vitro study tested the hypothesis that muscularis mucosae contractile activity contributes to rabbit colonic mucosal function by mechanisms other than simple mechanical deformation of the epithelium. Experiments were performed by using a technique that allows simultaneous recording of muscle activity and transmucosal potential difference, a measure of epithelial ion transport. ATP, brad...
متن کاملPhenotypic change of muscularis mucosae in early invasive colorectal adenocarcinoma.
BACKGROUND Invasive colorectal adenocarcinomas have bundles of eosinophilic spindle cells, which are regarded as myofibroblasts, in their desmoplastic stroma, some of which are continuous with the muscularis mucosa. AIM To investigate the relation between the eosinophilic spindle cells and the muscularis mucosa based on their cytoskeletal phenotypes in early invasive colorectal adenocarcinoma...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1988
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1988.tb11672.x